Department of Neurosurgery, Fujita Health University, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake 470-1192, Japan.
Neurosurg Rev. 2010 Jul;33(3):349-57; discussion 357. doi: 10.1007/s10143-010-0264-7. Epub 2010 May 21.
Although brain metastases are one of the most frequently diagnosed sequelae of systemic malignancy, their optimal management still is not well defined. In that respect, the different diagnostic and therapeutic approaches of BMs patients is an issue for serious discussions. The treatment options include surgical excision, WBRT, radiosurgery, chemotherapy, immunotherapy, etc. Nowadays, the aforementioned treatment modalities are usually combined in different treatment schemes. More than one option is used for the same patient and combining these treatment modalities gives better results than when separately use them. The value of surgical excision of progressing brain metastases treated with gamma knife surgery (GKS) is not well investigated.With the present study, we aim to investigate the value of surgical excision of symptomatic brain lesions that have been previously treated with GKS.
虽然脑转移是系统性恶性肿瘤最常见的后遗症之一，但它们的最佳治疗方法仍未得到明确界定。在这方面，脑转移瘤患者的不同诊断和治疗方法是一个需要认真讨论的问题。治疗选择包括手术切除、全脑放疗、立体定向放疗、化疗、免疫疗法等。如今，上述治疗方法通常结合在不同的治疗方案中。同一位患者会使用不止一种治疗方案，将这些治疗方法结合起来比单独使用时效果更好。对于用伽玛刀治疗后进展的脑转移瘤进行手术切除的价值尚未得到充分研究。本研究旨在探讨对先前用伽玛刀治疗的有症状脑病变进行手术切除的价值。
