McDermott Michael W, Sneed Penny K
Department of Neurosurgery, University of California, San Francisco, San Francisco, California 94143, USA.
Neurosurgery. 2005 Nov;57(5 Suppl):S45-53; discusssion S1-4. doi: 10.1227/01.neu.0000182741.82422.14.
Radiosurgery offers patients with brain metastases an effective and minimally invasive treatment modality. Radiosurgery provides local tumor control and prolongs survival in select patients with brain metastases. This review will discuss numerous aspects of radiosurgery, including the various delivery techniques and radiobiology. Treatment recommendations will be outlined in view of the available clinical data. Although surgery or radiosurgery with whole-brain radiotherapy remains an important option for patients with a solitary brain metastasis, radiosurgery with or without whole-brain radiotherapy should be considered in patients with a limited number of small tumors and a good prognosis.
放射外科为脑转移瘤患者提供了一种有效且微创的治疗方式。放射外科可实现局部肿瘤控制，并延长部分脑转移瘤患者的生存期。本综述将讨论放射外科的诸多方面，包括各种放疗技术和放射生物学。将根据现有临床数据概述治疗建议。尽管手术或全脑放疗联合放射外科仍是单发脑转移瘤患者的重要选择，但对于肿瘤数量有限且预后良好的患者，应考虑单纯放射外科或全脑放疗联合放射外科治疗。
