Department of Medicine, Georgetown University, 2233 Wisconsin Ave NW, Suite 214, Washington, DC 20007, USA.
AIDS Behav. 2011 Jan;15(1):9-15. doi: 10.1007/s10461-010-9710-3.
Serosorting, the practice of selectively engaging in unprotected sex with partners of the same HIV serostatus, has been proposed as a strategy for reducing HIV transmission risk among men who have sex with men (MSM). However, there is a paucity of scientific evidence regarding whether women engage in serosorting. We analyzed longitudinal data on women's sexual behavior with male partners collected in the Women's Interagency HIV Study from 2001 to 2005. Serosorting was defined as an increasing trend of unprotected anal or vaginal sex (UAVI) within seroconcordant partnerships over time, more frequent UAVI within seroconcordant partnerships compared to non-concordant partnerships, or having UAVI only with seroconcordant partners. Repeated measures Poisson regression models were used to examine the associations between serostatus partnerships and UAVI among HIV-infected and HIV-uninfected women. The study sample consisted of 1,602 HIV-infected and 664 HIV-uninfected women. Over the follow-up period, the frequency of seroconcordant partnerships increased for HIV-uninfected women but the prevalence of UAVI within seroconcordant partnerships remained stable. UAVI was reported more frequently within HIV seroconcordant partnerships than among serodiscordant or unknown serostatus partnerships, regardless of the participant's HIV status or types of partners. Among women with both HIV-infected and HIV-uninfected partners, 41% (63 HIV-infected and 9 HIV-uninfected) were having UAVI only with seroconcordant partners. Our analyses suggest that serosorting is occurring among both HIV-infected and HIV-uninfected women in this cohort.
血清学匹配，即选择性与 HIV 血清学状态相同的伴侣发生无保护性行为，被提议作为一种降低男男性行为者（MSM）中 HIV 传播风险的策略。然而，关于女性是否进行血清学匹配，科学证据很少。我们分析了 2001 年至 2005 年期间在妇女机构间 HIV 研究中收集的女性与男性伴侣性行为的纵向数据。血清学匹配被定义为随着时间的推移，在血清学一致的伴侣关系中无保护肛交或阴道交（UAVI）呈上升趋势，与非一致伴侣关系相比，在血清学一致的伴侣关系中 UAVI 更频繁，或者仅与血清学一致的伴侣发生 UAVI。重复测量泊松回归模型用于检查 HIV 感染和未感染妇女的血清学伴侣关系和 UAVI 之间的关联。研究样本包括 1602 名 HIV 感染和 664 名 HIV 未感染妇女。在随访期间，HIV 未感染妇女的血清学一致伴侣关系频率增加，但血清学一致伴侣关系内 UAVI 的流行率保持稳定。无论参与者的 HIV 状况或伴侣类型如何，血清学一致的 HIV 伴侣关系中报告的 UAVI 频率都高于血清学不一致或血清学状态未知的伴侣关系。在既有 HIV 感染又有 HIV 未感染伴侣的女性中，41%（63 名 HIV 感染和 9 名 HIV 未感染）仅与血清学一致的伴侣发生 UAVI。我们的分析表明，在该队列中，HIV 感染和未感染的女性都存在血清学匹配。
