血清状态披露对降低HIV传播风险的疗效。
The efficacy of serostatus disclosure for HIV Transmission risk reduction.
作者信息
O'Connell Ann A, Reed Sandra J, Serovich Julianne A
机构信息
Department of Educational Studies, The Ohio State University, Columbus, OH, USA.
出版信息
AIDS Behav. 2015 Feb;19(2):283-90. doi: 10.1007/s10461-014-0848-2.
Abstract
Interventions to assist HIV+ persons in disclosing their serostatus to sexual partners can play an important role in curbing rates of HIV transmission among men who have sex with men (MSM). Based on the methods of Pinkerton and Galletly (AIDS Behav 11:698-705, 2007), we develop a mathematical probability model for evaluating effectiveness of serostatus disclosure in reducing the risk of HIV transmission and extend the model to examine the impact of serosorting. In baseline data from 164 HIV+ MSM participating in a randomized controlled trial of a disclosure intervention, disclosure is associated with a 45.0 % reduction in the risk of HIV transmission. Accounting for serosorting, a 61.2 % reduction in risk due to disclosure was observed in serodisconcordant couples. The reduction in risk for seroconcordant couples was 38.4 %. Evidence provided supports the value of serostatus disclosure as a risk reduction strategy in HIV+ MSM. Interventions to increase serostatus disclosure and that address serosorting behaviors are needed.
摘要
帮助艾滋病毒呈阳性者向性伴侣披露其血清学状态的干预措施，在遏制男男性行为者（MSM）中艾滋病毒的传播率方面可发挥重要作用。基于平克erton和加勒特利的方法（《艾滋病行为》11:698 - 705，2007年），我们开发了一个数学概率模型，用于评估血清学状态披露在降低艾滋病毒传播风险方面的有效性，并扩展该模型以研究血清分类的影响。在参与一项披露干预随机对照试验的164名艾滋病毒呈阳性的男男性行为者的基线数据中，披露与艾滋病毒传播风险降低45.0%相关。考虑血清分类因素，在血清不一致的伴侣中，因披露导致的风险降低了61.2%。血清一致的伴侣中风险降低了38.4%。所提供的证据支持血清学状态披露作为艾滋病毒呈阳性的男男性行为者降低风险策略的价值。需要采取干预措施来增加血清学状态披露并应对血清分类行为。
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