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嵌入膜中的肉豆蔻酰化和非肉豆蔻酰化神经元钙传感器-1(NCS-1)的共振归属

Resonance assignments of myristoylated and non-myristoylated neuronal calcium sensor-1(NCS-1) embedded in a membrane.

作者信息

Chandra Kousik, Ramakrishnan Venkatesh, Sharma Yogendra, Chary K V R

机构信息

Department of Chemical Sciences, Tata Institute of Fundamental Research, Homi Bhabha Road, Colaba, Mumbai, 400005, India.

出版信息

Biomol NMR Assign. 2010 Oct;4(2):155-8. doi: 10.1007/s12104-010-9232-y. Epub 2010 May 20.

Abstract

Neuronal Calcium Sensor-1 (NCS-1) is a member of calcium sensor family. It is originally identified as frequenin. NCS-1 has been found to interact with membrane and cytosolic proteins and its physiological role is governed by N-terminal myristoylation. In this paper, we report the NMR assignments of both myristoylated and non-myristoylated NCS-1 in the presence of a membrane.

摘要

神经元钙传感器-1(NCS-1)是钙传感器家族的成员。它最初被鉴定为频率蛋白。已发现NCS-1与膜蛋白和胞质蛋白相互作用,其生理作用受N端肉豆蔻酰化调控。在本文中,我们报告了在有膜存在的情况下肉豆蔻酰化和非肉豆蔻酰化NCS-1的核磁共振(NMR)归属。

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