Department of Thoracic Medicine, The Royal Adelaide Hospital, Adelaide, South Australia, Australia.
Intern Med J. 2012 Mar;42(3):300-5. doi: 10.1111/j.1445-5994.2010.02261.x. Epub 2010 May 11.
Flexible fibre-optic bronchoscopy has become an essential investigation and is widely regarded as safe, but wider published prospective data regarding delayed complications are limited. There is continuing debate concerning the safety of proceduralist-administered sedation. We evaluated complication rates of bronchoscopy and proceduralist-administered sedation at our tertiary institution, and their clinical significance.
Prospective evaluation of all patients undergoing bronchoscopy over a 12-month period at a tertiary referral centre. Immediate minor and major complications were documented within 4 h of bronchoscopy, delayed complications at 48 h, case notes and bronchoscopy records were reviewed 1 month later.
Five hundred and fifty-eight flexible fibre-optic bronchoscopies were performed, 216 with transbronchial biopsy or nodal aspiration, 19 had therapeutic airways intervention. The minor complication rate at 4 h was 4.12% (23), rising to 26% (145) at 48 h. All 2.2% (12) major complications occurred exclusively within 4 h of bronchoscopy. No complications could be attributed to proceduralist-administered sedation.
Complication rates at 4 h were comparable with previously reported data. Delayed minor complications were greater than expected, and did not require additional medical input. There were no complications from proceduralist-administered sedation. Flexible fibre-optic bronchoscopy and proceduralist-administered sedation within our institution's guidelines are safe.
柔性纤维支气管镜检查已成为一项重要的检查手段,被广泛认为是安全的,但更广泛的关于延迟并发症的前瞻性数据有限。关于操作医生实施镇静的安全性仍存在争议。我们评估了我们的三级医疗机构支气管镜检查和操作医生实施镇静的并发症发生率及其临床意义。
前瞻性评估了三级转诊中心在 12 个月期间进行的所有支气管镜检查患者。在支气管镜检查后 4 小时内记录即刻轻微和严重并发症,在 48 小时时记录延迟并发症,1 个月后复查病历和支气管镜记录。
共进行了 558 例柔性纤维支气管镜检查,其中 216 例进行了经支气管活检或淋巴结抽吸,19 例进行了治疗性气道干预。4 小时时轻微并发症发生率为 4.12%(23 例),48 小时时上升至 26%(145 例)。所有 2.2%(12 例)的严重并发症仅发生在支气管镜检查后 4 小时内。没有并发症可归因于操作医生实施的镇静。
4 小时时的并发症发生率与先前报道的数据相当。延迟性轻微并发症发生率高于预期,但不需要额外的医疗干预。操作医生实施镇静无并发症。在我们机构的指南范围内,柔性纤维支气管镜检查和操作医生实施镇静是安全的。