Melby K, Gondrosen B, Gregusson S, Ribe H, Dahl O P
Department of Medical Microbiology, University Hospital, Tromsø, Norway.
Int J Food Microbiol. 1991 Feb;12(2-3):151-6. doi: 10.1016/0168-1605(91)90064-v.
A suspected waterborne outbreak of presumed campylobacteriosis involving approximately 680 of the 1000 inhabitants in a community is described. Twenty-two strains of Campylobacter jejuni were isolated from patients. Ten randomly chosen isolates were identified as biotype 1 LAU 0:1 (n = 9) and biotype 2 PEN 0:6, 7 (n = 1) and one from tap water as biotype 1 PEN 0:19, 22. The majority of cases occurred within a period of 1 week. Examination of human sera obtained during the first 2 weeks of the epidemic (n = 38) revealed two patients producing antibodies directed only against the water isolate. The majority (89%) of sera collected 4 weeks later (n = 18) had antibodies directed against the most common human isolate. We suggest that all three serotypes of C. jejuni were involved in this outbreak, stressing the need for continuous surveillance and treatment of public drinking water sources.
描述了一个社区中疑似水源性弯曲菌病暴发事件,该社区1000名居民中约680人受影响。从患者身上分离出22株空肠弯曲菌。随机选择的10株分离株被鉴定为生物型1 LAU 0:1(9株)和生物型2 PEN 0:6, 7(1株),从自来水中分离出的1株为生物型1 PEN 0:19, 22。大多数病例发生在1周内。对疫情前两周采集的人体血清(38份)进行检测,发现2名患者产生了仅针对水源分离株的抗体。4周后采集的血清(18份)中,大多数(89%)含有针对最常见人体分离株的抗体。我们认为此次暴发涉及空肠弯曲菌的所有三种血清型,强调了对公共饮用水源进行持续监测和处理的必要性。