Oslo University Hospital, PPU, Dikemark, 1385 Asker, Norway.
Res Dev Disabil. 2010 Nov-Dec;31(6):1669-77. doi: 10.1016/j.ridd.2010.04.009. Epub 2010 May 20.
Few studies assess psychiatric disorders in representative samples of individuals with autism and ID. Symptoms of autism and psychiatric disorders have been confounded. PAC, a conceptually analysed and validated screening instrument, was used.
Assess prevalence of psychiatric disorders in individuals with intellectual disability only (ID-only) and with combination of autism and ID (autism). Sixty-two (autism) and 132 (ID-only) participants were screened for psychiatric disorders with the Psychopathology in Autism Checklist (PAC); included general adjustment problems (GAP), and severe adjustment problems (SGAP) in one county in Norway. Psychosis, depression, anxiety, and OCD were addressed. Both SGAP and a high psychiatric disorder score were required to screen a psychiatric disorder. "Diagnostic overlap" was defined as more than one psychiatric disorder concurrent with autism. Psychiatric disorders and SGAP were found to be high both in the autism (53.2%) and ID-only group (17.4%). More than 50% of the autism and approximately 20% of ID-only group had SGAP. The differences were significant. The autism-psychiatric disorder interaction was significant. The largest differences between the prevalence in the autism and the ID-only group were shown in individuals with anxiety. The majority of the individuals in both study groups were afflicted with more than one psychiatric disorder. About 60% were found to have more than one disorder. The individuals with more severe psychiatric symptoms had higher degrees of diagnostic overlap. Having an intellectual disability seem to imply high risk for developing adjustment problems, and it seems especially difficult for individuals with autism to master every-day challenges.
很少有研究评估自闭症和智力障碍个体中有代表性样本中的精神疾病。自闭症和精神疾病的症状已经混淆。使用了概念上经过分析和验证的筛选工具 PAC。
评估仅智力障碍(ID-only)和自闭症与智力障碍合并(自闭症)个体中精神疾病的患病率。62 名(自闭症)和 132 名(ID-only)参与者在挪威一个县使用自闭症检查表(PAC)筛查精神疾病;包括一般适应问题(GAP)和严重适应问题(SGAP)。探讨了精神病、抑郁、焦虑和强迫症。只有 SGAP 和高精神疾病评分才能筛查出精神疾病。“诊断重叠”定义为自闭症并发一种以上的精神疾病。在自闭症(53.2%)和 ID-only 组(17.4%)中都发现 SGAP 和精神疾病发生率很高。自闭症和 ID-only 组中超过 50%的个体存在 SGAP。差异具有统计学意义。自闭症与精神疾病的相互作用具有统计学意义。在焦虑症患者中,自闭症和 ID-only 组的患病率差异最大。两组研究对象中大多数人都患有一种以上的精神疾病。大约 60%的人发现有超过一种障碍。精神疾病症状较严重的个体,诊断重叠的程度更高。智力障碍似乎意味着出现适应问题的风险更高,而对于自闭症患者来说,掌握日常生活的挑战似乎尤其困难。