Department of Plant Sciences, School of Life Sciences, University of Hyderabad, Hyderabad, India.
Trends Plant Sci. 2010 Jul;15(7):395-401. doi: 10.1016/j.tplants.2010.04.006. Epub 2010 May 20.
Plant productivity is continuously challenged by pathogen attack and abiotic stress such as drought and salt stress. The phytohormone abscisic acid (ABA) is a key endogenous messenger in plants' responses to such stresses and understanding ABA signalling is essential for improving plant performance in the future. Since the discovery of ABA as a leaf abscission- and seed dormancy-promoting sesquiterpenoid in the 1960s, our understanding of the action of the phytohormone ABA has come a long way. Recent breakthroughs in the field of ABA signalling now unfold a unique hormone perception mechanism where binding of ABA to the ABA receptors RCARs/PYR1/PYLs leads to inactivation of type 2C protein phosphatases such as ABI1 and ABI2. The protein phosphatases seem to function as coreceptors and their inactivation launches SNF1-type kinase action which targets ABA-dependent gene expression and ion channels.
植物的生产力不断受到病原体攻击和非生物胁迫（如干旱和盐胁迫）的挑战。脱落酸（ABA）作为一种关键的内源性信号分子，参与植物对这些胁迫的响应，因此，深入了解 ABA 信号转导对于提高植物的未来表现至关重要。自 20 世纪 60 年代发现 ABA 作为一种促进叶片脱落和种子休眠的倍半萜以来，我们对植物激素 ABA 的作用有了更深入的了解。最近在 ABA 信号领域的突破揭示了一种独特的激素感知机制，ABA 与 ABA 受体 RCARs/PYR1/PYLs 的结合导致 2C 型蛋白磷酸酶（如 ABI1 和 ABI2）的失活。蛋白磷酸酶似乎作为共受体发挥作用，其失活启动 SNF1 型激酶的作用，靶向 ABA 依赖的基因表达和离子通道。
