Peng Zhi-Yu, Gan Lu, Xue Kang, Sodhi Akrit, Ye Xiao-Feng, Ren Hui, Qian Jiang
Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai 200031, China.
Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai 200031, China.
Int J Ophthalmol. 2023 Feb 18;16(2):233-237. doi: 10.18240/ijo.2023.02.09. eCollection 2023.
To characterize spectral-domain optical coherence tomography (SD-OCT) features of chorioretinal folds in orbital mass imaged using enhanced depth imaging (EDI).
Prospective observational case-control study was conducted in 20 eyes of 20 patients, the uninvolved eye served as a control. All the patients underwent clinical fundus photography, computed tomography, EDI SD-OCT imaging before and after surgery. Two patients with cavernous hemangiomas underwent intratumoral injection of bleomycin A5; the remaining patients underwent tumor excision. Patients were followed 1 to 14mo following surgery (average follow up, 5.8mo).
Visual acuity prior to surgery ranged from 20/20 to 20/200. Following surgery, 5 patients' visual acuity remained unchanged while the remaining 15 patients had a mean letter improvement of 10 (range 4 to 26 letters). Photoreceptor inner/outer segment defects were found in 10 of 15 patients prior to surgery. Following surgical excision, photoreceptor inner/outer segment defects fully resolved in 8 of these 10 patients.
Persistence of photoreceptor inner/outer segment defects caused by compression of the globe by an orbital mass can be associated with reduced visual prognosis. Our findings suggest that photoreceptor inner/outer segment defects on EDI SD-OCT could be an indicator for immediate surgical excision of an orbital mass causing choroidal compression.
利用增强深度成像（EDI）对眼眶肿物成像，以表征脉络膜视网膜皱褶的频域光学相干断层扫描（SD-OCT）特征。
对20例患者的20只眼进行前瞻性观察性病例对照研究，未受累眼作为对照。所有患者在手术前后均接受了临床眼底照相、计算机断层扫描、EDI SD-OCT成像。2例海绵状血管瘤患者接受瘤内注射博来霉素A5；其余患者接受肿瘤切除。术后对患者进行1至14个月的随访（平均随访5.8个月）。
术前视力范围为20/20至20/200。术后，5例患者视力保持不变，其余15例患者平均视力提高了10个字母（范围为4至26个字母）。术前15例患者中有10例发现光感受器内/外节缺损。手术切除后，这10例患者中有8例光感受器内/外节缺损完全消失。
眼眶肿物压迫眼球导致的光感受器内/外节缺损持续存在可能与视力预后降低有关。我们的研究结果表明，EDI SD-OCT上的光感受器内/外节缺损可能是立即手术切除引起脉络膜压迫的眼眶肿物的一个指标。
