Kodell R L, Chen J J
National Center for Toxicological Research, Jefferson, Arkansas 72079.
Biometrics. 1991 Mar;47(1):139-46.
A method is proposed for classifying various experimental outcomes associated with statistically significant trend tests according to a set of sequential testing within a family of closed (under intersections) one-sided tests. The intent of the procedure is to characterize the general shape of implied dose-response relationships, taking care neither to inflate the false-positive (Type I) error rate by overtesting, nor to sacrifice power by overadjusting for multiple comparisons.
