Department of Biological Chemistry & Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.
Bioinformatics. 2010 Jul 15;26(14):1806-7. doi: 10.1093/bioinformatics/btq265. Epub 2010 May 21.
Computational gene function prediction can serve to focus experimental resources on high-priority experimental tasks. FuncBase is a web resource for viewing quantitative machine learning-based gene function annotations. Quantitative annotations of genes, including fungal and mammalian genes, with Gene Ontology terms are accompanied by a community feedback system. Evidence underlying function annotations is shown. For example, a custom Cytoscape viewer shows functional linkage graphs relevant to the gene or function of interest. FuncBase provides links to external resources, and may be accessed directly or via links from species-specific databases.
FuncBase as well as all underlying data and annotations are freely available via http://func.med.harvard.edu/
计算基因功能预测可用于将实验资源集中在高优先级的实验任务上。FuncBase 是一个用于查看基于定量机器学习的基因功能注释的网络资源。具有基因本体论术语的基因（包括真菌和哺乳动物基因）的定量注释伴随着社区反馈系统。显示了功能注释的依据。例如，自定义 Cytoscape 查看器显示与基因或功能相关的功能链接图。FuncBase 提供了指向外部资源的链接，可直接访问，也可通过特定于物种的数据库中的链接访问。
FuncBase 以及所有基础数据和注释均可通过 http://func.med.harvard.edu/ 免费获得。
