Kim P T, Carter E M, Hubert J J
Department of Mathematics and Statistics, University of Guelph, Ontario, Canada.
Biometrics. 1991 Mar;47(1):295-301.
This paper exhibits a closed-form point and interval estimator of the log relative potency that incorporates prior information on the log relative potency in a symmetric parallel line bioassay. The point estimator turns out to be a weighted average of the usual estimator and the prior mean where the weights are determined by the prior variance.
本文展示了对数相对效价的闭式点估计和区间估计,该估计在对称平行线生物测定中纳入了关于对数相对效价的先验信息。结果表明,点估计是通常估计值与先验均值的加权平均值,其中权重由先验方差确定。