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解读DNA血统检测的含义。

Interpreting the implications of DNA ancestry tests.

作者信息

Wagner Jennifer K

机构信息

Department of Anthropology, Pennsylvania State University, University Park, PA 16802, USA.

出版信息

Perspect Biol Med. 2010 Spring;53(2):231-48. doi: 10.1353/pbm.0.0158.

Abstract

Shopping for genetic information has become popular, but consumers may not understand what exactly they are buying. The retail DNA industry is forcing laypersons, academics, and medical and legal professionals alike to face the crossroads of genetics, law, and society. How will we decipher the meanings of the tests, determine the value of the information provided, or appropriately encourage or discourage various applications of that genetic information? When it comes to understanding the signs at the crossroads of disciplines, something is always potentially lost in translation. This article provides an overview of the retail DNA industry, addressing a few questions ripe for misinterpretation and confusion. It argues that the challenges posed by the retail DNA industry are both intelligible and manageable; optimally, multidisciplinary individuals would guide the way, steering the courts, legislature, laboratories, and clinics toward an adequate balance of consumer protection, autonomy, and understanding.

摘要

购买基因信息已变得流行起来,但消费者可能并不确切明白他们究竟购买的是什么。零售DNA行业正迫使外行人、学者以及医学和法律专业人士都面临遗传学、法律和社会的十字路口。我们将如何解读检测结果的含义,确定所提供信息的价值,或者适当地鼓励或劝阻该基因信息的各种应用呢?当涉及到理解学科交叉路口的标识时,翻译过程中总会有一些潜在的信息丢失。本文概述了零售DNA行业,探讨了一些容易产生误解和混淆的问题。文章认为,零售DNA行业带来的挑战是可以理解和应对的;最理想的情况是,多学科专业人士将引领方向,引导法院、立法机构、实验室和诊所实现消费者保护、自主权和理解之间的适当平衡。

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