Villa Diego, Knowling Meg
Division of Medical Oncology, Department of Internal Medicine, University of British Columbia, Vancouver, Canada.
J Pediatr Hematol Oncol. 2010 Jul;32(5):e210-2. doi: 10.1097/MPH.0b013e3181dce311.
Two young adults had similar presentations of Ewing sarcoma, with spinal cord involvement and significant neurologic deficits. Shortly after workup, stabilization, and initiation of chemotherapy, both developed acute saddle pulmonary embolism, despite prophylactic anticoagulation. In both cases, prompt intravenous thrombolysis and therapeutic anticoagulation successfully managed this complication. Review of the presentation, treatment options, and most current guidelines for acute saddle pulmonary embolism follow the case presentations.
两名年轻成人患有相似表现的尤因肉瘤，伴有脊髓受累和明显的神经功能缺损。在进行检查、病情稳定并开始化疗后不久，尽管进行了预防性抗凝治疗，两人均发生了急性鞍状肺栓塞。在这两例病例中，及时的静脉溶栓和治疗性抗凝成功地处理了这一并发症。在病例介绍之后，将回顾急性鞍状肺栓塞的临床表现、治疗选择和最新指南。
