一名患有贝克威思-维德曼综合征的新生儿同时发生胰腺母细胞瘤和神经母细胞瘤。

Simultaneous occurrence of pancreatoblastoma and neuroblastoma in a newborn with beckwith-wiedemann syndrome.

作者信息

Sorrentino Stefania, Conte Massimo, Nozza Paolo, Granata Claudio, Capra Valeria, Avanzini Stefano, Garaventa Alberto

机构信息

Department of Hematology-Oncology, Gaslini Children's Hospital, Genoa, Italy.

出版信息

J Pediatr Hematol Oncol. 2010 Jul;32(5):e207-9. doi: 10.1097/MPH.0b013e3181dccd1e.

DOI:10.1097/MPH.0b013e3181dccd1e

PMID:20495482

Abstract

Beckwith-Wiedemann syndrome is associated with an increased risk of tumors in the pediatric age. We report the case of a newborn with Beckwith-Wiedemann syndrome presenting the simultaneous occurrence of a cystic pancreatoblastoma and an adrenal neuroblastoma. Surgery was required to treat the pancreatoblastoma, and a "wait and see" policy was adopted for the neuroblastoma, which spontaneously regressed within a few months.

摘要

贝克威思-维德曼综合征与儿童期肿瘤风险增加有关。我们报告了一例患有贝克威思-维德曼综合征的新生儿，同时发生了囊性胰腺母细胞瘤和肾上腺神经母细胞瘤。需要手术治疗胰腺母细胞瘤，对于神经母细胞瘤则采取“观察等待”策略，该肿瘤在几个月内自行消退。