蒽酮与烯酮的不对称有机催化迈克尔加成。

Asymmetric organocatalytic Michael addition of anthrone to enone.

机构信息

Engineering Research Centre of Pharmaceutical Process Chemistry, Ministry of Education, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China.

出版信息

Org Biomol Chem. 2010 Jul 21;8(14):3244-50. doi: 10.1039/b927421a. Epub 2010 May 21.

DOI:10.1039/b927421a

PMID:20495718

Abstract

Catalyzed by the bifunctional tertiary amino-thiourea organocatalyst derived from epicinchona alkaloid, the asymmetric Michael addition of anthrone to enone was achieved in high yield with excellent enantioselectivity.

摘要

受来源于金鸡纳生物碱的双功能叔胺-硫脲有机催化剂的催化，蒽酮与烯酮的不对称迈克尔加成以高产率和优异的对映选择性实现。