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与口服双膦酸盐相关的颌骨坏死相关的种植体失败。

Implant failure associated with oral bisphosphonate-related osteonecrosis of the jaw.

作者信息

Shin Eun-Young, Kwon Young-Hyuk, Herr Yeek, Shin Seung-Il, Chung Jong-Hyuk

机构信息

Department of Periodontology, Kyung Hee University School of Dentistry, Seoul, Korea.

出版信息

J Periodontal Implant Sci. 2010 Apr;40(2):90-5. doi: 10.5051/jpis.2010.40.2.90. Epub 2010 Apr 15.

Abstract

PURPOSE

The aim of this study is to report a case of oral bisphosphonate-related osteonecrosis of the jaw (BRONJ) resulting in implant failure.

METHODS

A patient suspected of having BRONJ was referred to the Department of Periodontology, Kyung Hee University School of Dentistry for the evaluation and treatment of exposed bone around implants.

RESULTS

The patient, who had been taking oral bisphosphonates (BPs) for about a year, was successfully treated with systemic antibiotics, chlorhexidine mouth rinse, explantation, and surgical debridement of necrotic bone.

CONCLUSIONS

The results of this case suggest that a patient taking BPs orally should be treated cautiously. Appropriate management including cessation of BPs and respective dental treatment may reduce the development of BRONJ.

摘要

目的

本研究旨在报告一例因口服双膦酸盐导致颌骨坏死(BRONJ)并致使种植失败的病例。

方法

一名疑似患有BRONJ的患者被转诊至庆熙大学牙科学院牙周病科,以评估和治疗种植体周围暴露的骨组织。

结果

该患者口服双膦酸盐(BPs)约一年,通过全身使用抗生素、洗必泰漱口水、取出种植体以及对坏死骨进行手术清创,成功得到治疗。

结论

该病例结果表明,口服BPs的患者应谨慎治疗。包括停用BPs及相应的牙科治疗在内的适当管理措施可能会减少BRONJ的发生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ceb/2872811/c896ed25f4b2/jpis-40-90-g001.jpg

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