Department of Surgery, Loyola University Medical Center, Maywood, IL 60153, USA.
J Gastrointest Surg. 2010 Sep;14(9):1434-41. doi: 10.1007/s11605-010-1233-8. Epub 2010 May 25.
Several studies have confirmed that gastroesophageal reflux disease (GERD) in lung transplant patients is a risk factor for the development and progression of bronchiolitis obliterans syndrome (BOS), a form of rejection after lung transplantation. Moreover, numerous reports indicate that surgical correction of GERD may control the decline in lung function characteristic of BOS. Although laparoscopic fundoplication is an accepted treatment option for these patients with GERD, the surgical technique, which often includes a laparoscopic pyloroplasty, has not been standardized.
The purpose of this article is to describe a step-by-step approach to the laparoscopic treatment of GERD in lung transplant patients. We also address specific technical concerns encountered in the surgical management of this high-risk patient population; we provide data on the safety of this operation; and we illustrate the evidence-based rationale for each technical step of the procedure.
多项研究证实,肺移植患者的胃食管反流病(GERD)是发生和发展气道闭塞性细支气管炎综合征(BOS)的一个风险因素,BOS 是肺移植后的一种排斥反应形式。此外,大量报告表明,GERD 的手术矫正可能会控制 BOS 特有的肺功能下降。尽管腹腔镜胃底折叠术是 GERD 这些患者的一种公认的治疗选择,但通常包括腹腔镜幽门成形术的手术技术尚未标准化。
本文的目的是描述一种针对肺移植患者 GERD 的腹腔镜治疗的分步方法。我们还解决了在这一高风险患者群体的手术管理中遇到的特定技术问题;我们提供了有关该手术安全性的数据;并说明了该手术步骤的每个技术步骤的循证原理。