Fung Hin Tat, Lam Ka Keung, Wong Oi Fung, Lam Tommy Shing Kit
Accident and Emergency Department, Tuen Mun Hospital, Hong Kong, China.
J Med Toxicol. 2010 Jun;6(2):147-9. doi: 10.1007/s13181-010-0068-8.
We report a case of local antivenom therapy for ocular exposure to the venom of Naja atra. An 83-year-old woman sustained conjunctival and corneal injuries by the venom of a spitting N. atra. Local instillation of N. naja antivenom quickly relieved the pain as measured by visual analog scale, and she recovered uneventfully. Good recovery ensuing topical antivenom administration for ocular exposure to the venom of spitting N. atra and Naja nigricollis has been described in literature, but the pain response was not thoroughly documented. The mechanism of antivenom for pain relief remains to be established. In light of the associated positive outcome observed in human, the role of ocular antivenom therapy merits further study.
我们报告了一例针对眼镜蛇毒液眼部暴露进行局部抗蛇毒血清治疗的病例。一名83岁女性因被喷毒眼镜蛇的毒液导致结膜和角膜损伤。通过视觉模拟评分法测量,局部滴注眼镜蛇抗蛇毒血清迅速缓解了疼痛,她最终顺利康复。文献中已描述了局部应用抗蛇毒血清治疗眼镜蛇和黑颈眼镜蛇毒液眼部暴露后取得良好恢复的情况,但疼痛反应并未得到充分记录。抗蛇毒血清缓解疼痛的机制仍有待确定。鉴于在人类身上观察到的相关积极结果,眼部抗蛇毒血清治疗的作用值得进一步研究。