Department of Biomedical Sciences and Engineering, Faculty of Health Sciences, Graduate School of Health Sciences, Hokkaido University, Sapporo, Japan.
Yonsei Med J. 2010 Jul;51(4):557-61. doi: 10.3349/ymj.2010.51.4.557.
Deciding on treatment carcinoma of the tongue when the tumor has a thickness of 1.5 cm or more is difficult. Surgery often requires wide resection and re-construction, leading to considerable functional impairment. A cesium implant is an attractive option, but according to the Manchester System, a two plane implant is needed.
According to the textbook, a tumor is sandwiched between the needles, which are implanted at the edge of the tumor. This may cause an unnecessarily high dose to the outer surface of the tongue, which sometimes leads to a persistent ulcer. To avoid this complication, we invented a modified implantation method, and applied the method to five consecutive patients.
With a minimum follow-up of 2 years, all primary tumors in 5 consecutive patients have been controlled. No complications occurred in soft tissue of the tongue or in the mandible.
Our modified Manchester System was feasible and effective for tumors that has a thickness of 1.5 cm or more.
当肿瘤厚度达到或超过 1.5 厘米时,决定如何治疗舌癌较为困难。手术通常需要广泛切除和重建,从而导致严重的功能损伤。铯植入物是一种很有吸引力的选择,但根据曼彻斯特系统,需要进行两平面植入。
根据教科书,将肿瘤夹在位于肿瘤边缘的针之间进行植入。这可能会导致舌的外表面接受不必要的高剂量,有时会导致持续的溃疡。为了避免这种并发症,我们发明了一种改良的植入方法,并将该方法应用于五例连续患者。
5 例连续患者的最小随访时间均为 2 年,所有原发性肿瘤均得到控制。舌部软组织和下颌骨均未发生并发症。
我们改良的曼彻斯特系统对于厚度达到或超过 1.5 厘米的肿瘤是可行且有效的。