Annear Matthew J, Wilkie David A, Gemensky-Metzler Anne J
Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, MI, USA.
Vet Ophthalmol. 2010 May;13(3):204-9. doi: 10.1111/j.1463-5224.2010.00779.x.
To evaluate the outcome of diode laser transscleral cyclophotocoagulation (TSCP) for the treatment of glaucoma in horses.
Medical records at The Ohio State University were reviewed. All horses that underwent diode laser TSCP between the years of 1995 and 2007 were included. Preoperative, procedural and clinical follow-up data were collected, and telephone follow-up was performed.
Forty-two eyes of 36 horses were included. Twenty-four hours prior to surgery mean intraocular pressure (IOP) was 37.17 + or - 13.48 mmHg (42 eyes). Forty-one of 42 eyes (98%) were sighted and 39 of 39 (100%) of eyes were receiving topical glaucoma medication. At 3-5 weeks postoperatively the average IOP was 19.36 + or - 12.04 mmHg (22 eyes). IOP remained significantly lower than pretreatment values at all periods of clinical follow-up (P < 0.05). There was no significant difference in vision outcome, or the requirement for topical glaucoma medication relative to pretreatment values at any follow-up period. Hyphema in 5 of 42 eyes was the only complication noted. Of the 27 eyes seen for clinical follow-up, 2 were enucleated because of refractory elevation of IOP. Mean telephone follow-up was 49 months. Twenty-one of 22 owners contacted (95%) reported that the treatment had been of value, 14 of 22 eyes (64%) were receiving topical glaucoma medication, and 13 of 22 eyes (59%) were considered sighted.
Diode laser TSCP aided in the control of IOP and maintenance of vision but did not eliminate the need for topical glaucoma medication during the period of clinical follow-up.
评估二极管激光经巩膜睫状体光凝术(TSCP)治疗马青光眼的效果。
回顾俄亥俄州立大学的病历。纳入1995年至2007年间接受二极管激光TSCP治疗的所有马匹。收集术前、手术过程及临床随访数据,并进行电话随访。
纳入36匹马的42只眼。手术前24小时平均眼压(IOP)为37.17±13.48 mmHg(42只眼)。42只眼中有41只(98%)有视力,39只眼中有39只(100%)正在使用局部青光眼药物治疗。术后3 - 5周平均眼压为19.36±12.04 mmHg(22只眼)。在所有临床随访期间,眼压仍显著低于治疗前值(P < 0.05)。在任何随访期,视力结果或局部青光眼药物治疗需求与治疗前值相比均无显著差异。42只眼中有5只出现前房积血是唯一记录到的并发症。在接受临床随访的27只眼中,有2只因眼压难治性升高而被摘除眼球。平均电话随访时间为49个月。联系的22位主人中有21位(95%)报告该治疗有价值,22只眼中有14只(64%)正在使用局部青光眼药物治疗,22只眼中有13只(59%)被认为有视力。
二极管激光TSCP有助于控制眼压和维持视力,但在临床随访期间并未消除使用局部青光眼药物治疗的必要性。