On a possible mechanism of abnormal brain development in experimental hyperphenylalaninemia.
作者信息
Hommes F A, Matsuo K
机构信息
Department of Cell and Molecular Biology, Medical College of Georgia, Augusta, GA 30912-3331, U.S.A.
出版信息
Neurochem Int. 1987;11(1):1-10. doi: 10.1016/0197-0186(87)90141-0.
PMID:20501135
Abstract
It has been observed that high levels of phenylalanine inhibit the synthesis of sulfatides in brain. A possible scenario leading to a decreased number of synaptic contacts in the adult is developed as an explanation for brain dysfunction. The evidence for each of the steps of this scenario is reviewed.
摘要
Zotero 插件