Institute of Diagnostic, Interventional and Pediatric Radiology Inselspital, University of Bern Freiburgstrasse 10, Bern CH-3010, Switzerland.
Radiology. 2010 Jun;255(3):667-8. doi: 10.1148/radiol.100211.
In an experimental murine model of unilateral ureteral obstruction, Togao et al demonstrated that diffusion-weighted (DW) magnetic resonance (MR) imaging can depict and enable monitoring of abnormal changes in the progression of renal fibrosis; because these microstructural changes are complex and multifactorial, future studies focused on their specificity should be performed before they are applied in clinical trials.
在单侧输尿管梗阻的实验性小鼠模型中，Togao 等人证明扩散加权（DW）磁共振（MR）成像可以描绘和监测肾脏纤维化进展中的异常变化；由于这些微观结构变化复杂且多因素，在将其应用于临床试验之前，应进行针对其特异性的进一步研究。
