使用洛哌丁胺治疗的腹泻患者出现坏死性结肠炎并伴有穿孔。
Necrotising colitis with perforation in diarrhoic patients treated with loperamide.
作者信息
Olm M, Gonzalez F J, Garcia-Valdecasas J C, Fuster J, Bertran A, Milla J
机构信息
Internal Medicine Unit, Hospital Clinico y Provincial, Barcelona, Spain.
出版信息
Eur J Clin Pharmacol. 1991;40(4):415-6. doi: 10.1007/BF00265854.
PMID:2050178
Abstract
Two cases of necrotising enterocolitis with perforation occurred in patients with paralytic ileus after loperamide therapy. The possible role of loperamide in the pathogenesis of the complications is suggested.
摘要
在洛哌丁胺治疗后发生麻痹性肠梗阻的患者中出现了两例坏死性小肠结肠炎伴穿孔的病例。提示了洛哌丁胺在这些并发症发病机制中的可能作用。
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