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围产期心肌病

Peripartum cardiomyopathy.

作者信息

Ramaraj R

机构信息

Department of Internal Medicine, University of Arizona, Tucson, AZ 85724, USA.

出版信息

Minerva Ginecol. 2010 Apr;62(2):129-36.

Abstract

Peripartum cardiomyopathy (PPCM) is a life-threatening condition of unknown cause that occurs in previously healthy women during the peripartum period. It is characterized by left ventricular (LV) dysfunction and symptoms of heart failure which occurs between the last trimester of pregnancy and the first five months of the postpartum period. Recent reports show that the mortality rate in the United States due to PPCM is much lower than previously reported and the LV systolic function recovery rates are now >50%. This review identifies the possible causes of PPCM and ways to recognize and manage these patients. Patients with PPCM often present with heart failure and therefore standard treatment for heart failure is recommended. Depending on the recovery of ventricular function subsequent pregnancies carry a higher risk of relapse of PPCM.

摘要

围产期心肌病(PPCM)是一种病因不明的危及生命的疾病,发生在既往健康的女性围产期。其特征为左心室(LV)功能障碍和心力衰竭症状,出现于妊娠晚期至产后头五个月之间。近期报告显示,美国因PPCM导致的死亡率远低于先前报告的水平,且左心室收缩功能恢复率目前>50%。本综述确定了PPCM的可能病因以及识别和管理这些患者的方法。PPCM患者常表现为心力衰竭,因此建议采用心力衰竭的标准治疗方法。根据心室功能的恢复情况,后续妊娠时PPCM复发的风险更高。

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