Department of Chemistry, College of Chemistry and Chemical Engineering, and State Key Laboratory for Physical Chemistry of Solid Surfaces, Xiamen University, Xiamen 361005, Fujian, P. R. China.
Org Biomol Chem. 2010 Jul 21;8(14):3259-66. doi: 10.1039/c002093a. Epub 2010 May 25.
Three different substituted thiazoles have been successfully synthesized from readily available propargylic alcohols. Various secondary propargylic alcohols or tertiary propargylic alcohols participated well in the reaction, providing the desired products in good yields. This method provides a flexible and rapid route to substituted thiazoles.
三种不同取代的噻唑已经成功地从易得的丙炔醇合成而来。各种仲丙炔醇或叔丙炔醇在反应中都很好地参与,以良好的产率提供了所需的产物。该方法为取代噻唑提供了一种灵活快速的途径。