Department of Veteran Affairs Rehabilitation Research and Development Brain Rehabilitation Research Center at the Malcom Randall VA Medical Center, Gainesville, Florida, USA.
Brain Imaging Behav. 2010 Jun;4(2):121-31. doi: 10.1007/s11682-010-9091-2.
Little is known regarding the differences in active cortical and subcortical systems during opposing movements of an agonist-antagonist muscle group. The objective of this study was to characterize the differences in cortical activation during active ankle dorsiflexion and plantarflexion using functional MRI (fMRI). Eight right-handed healthy adults performed auditorily cued right ankle dorsiflexions and plantarflexions during fMRI. Differences in activity patterns between dorsiflexion and plantarflexion during fMRI were assessed using between- and within-subject voxel-wise t-tests. Results indicated that ankle dorsiflexion recruited significantly more regions in left M1, the supplementary motor area (SMA) bilaterally, and right cerebellum. Both movements activated similar left hemisphere regions in the putamen and thalamus. Dorsiflexion activated additional areas in the right putamen. Results suggest that ankle dorsiflexion and plantarflexion may be controlled by both shared and independent neural circuitry. This has important implications for functional investigations of gait pathology and how rehabilitation may differentially affect each movement.
关于在拮抗肌群组进行相反运动时主动皮质和皮质下系统的差异，人们知之甚少。本研究的目的是使用功能磁共振成像（fMRI）来描述主动踝关节背屈和跖屈时皮质激活的差异。8 名右利手健康成年人在 fMRI 期间进行听觉提示的右踝背屈和跖屈。使用基于体素的组间和组内 t 检验评估 fMRI 期间背屈和跖屈之间的活动模式差异。结果表明，背屈时左侧 M1、双侧运动辅助区（SMA）和右侧小脑的激活区域明显多于跖屈。两种运动都激活了左侧壳核和丘脑的相似区域。背屈还激活了右侧壳核的其他区域。结果表明，踝关节背屈和跖屈可能由共享和独立的神经回路控制。这对步态病理的功能研究以及康复如何对每种运动产生不同的影响具有重要意义。
