Translational Cancer Research Group and Pathology Department, Cancer Center of the Saint-Augustinus Hospital, University of Antwerp, Wilrijk, Belgium.
Cancer. 2010 Jun 1;116(11 Suppl):2748-54. doi: 10.1002/cncr.25169.
This objective of the current review was to provide the reader with a comprehensive summary of the literature related to 3 important and inter-related features of the biology of inflammatory breast cancer (IBC): angiogenesis, lymphangiogenesis, and the formation of tumor emboli. Information derived from animal models of IBC as well as from translational studies using tissue samples of patients with IBC are discussed.
本次综述的目的是为读者提供有关炎症性乳腺癌(IBC)生物学中三个重要且相互关联的特征的文献综述:血管生成、淋巴管生成和肿瘤栓子的形成。讨论了来自 IBC 动物模型的信息以及使用 IBC 患者组织样本进行的转化研究。