El-Hakam Lisa Michael, Volpi John, Mawad Michel, Clark Gary
Department of Pediatric Neurology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas 77030, USA.
J Child Neurol. 2010 Oct;25(10):1278-83. doi: 10.1177/0883073809357471. Epub 2010 May 26.
Moyamoya vasculopathy is a progressive, occlusive vasculopathy leading to ischemic and hemorrhagic strokes. No treatments are established to treat acute ischemic stroke with moyamoya vasculopathy. A 3-year-old girl with moyamoya syndrome developed acute left hemiplegia. Emergent angiography showed near-occlusion of the supraclinoid segment of the right internal carotid artery. Balloon angioplasty was performed within 6 hours of symptom onset, with significant improvement in the child's neurological symptoms. This is the youngest case of intracranial balloon angioplasty, and this article discusses the paucity of data regarding angioplasty and other forms of endovascular intervention in pediatric cerebrovascular disease and moyamoya vasculopathy. Further study is needed to determine the safety and efficacy of endovascular intervention in these diseases.
烟雾病血管病变是一种进行性闭塞性血管病变,可导致缺血性和出血性中风。目前尚无针对烟雾病血管病变所致急性缺血性中风的确立治疗方法。一名患有烟雾病综合征的3岁女孩出现急性左偏瘫。急诊血管造影显示右侧颈内动脉床突上段近乎闭塞。在症状发作6小时内进行了球囊血管成形术,患儿神经症状有显著改善。这是颅内球囊血管成形术最年轻的病例,本文讨论了儿科脑血管疾病和烟雾病血管病变中关于血管成形术及其他形式血管内介入的数据匮乏情况。需要进一步研究以确定血管内介入在这些疾病中的安全性和有效性。