Wild J M, Johnston B M, Gluckman P D
Department of Anatomy, University of Auckland School of Medicine, New Zealand.
J Anat. 1991 Apr;175:105-29.
Injections of WGA-HRP and CTB-HRP were made into the cervical vagus or the nodose ganglion in a series of lambs, in order to define the sensory projections and motor origins of the vagus nerve. Injections into the nodose ganglion were much more successful than injections into the cervical vagus in effecting the desired result. The former produced labelling of both descending and ascending components of the solitary tract (TS). The descending component terminated massively in all ipsilateral and certain contralateral subnuclei of the nucleus of the solitary tract (nTS) and in the upper cervical spinal cord. Patchy terminations were also observed within the interpolated subnucleus of the nucleus of the spinal trigeminal tract, and within Lamina I of the upper cervical cord. The ascending component of TS terminated in rostral regions of the nTS, and in specific portions of the principal sensory trigeminal nucleus and the lateral parabrachial and Kölliker-Fuse nuclei. The motor origins of the vagus nerve arose almost completely ipsilaterally in the dorsal motor nucleus of the vagus, the nucleus ambiguus, and the caudal portion of the nucleus retroambiguus situated in the lateral part of the intermediate grey at upper cervical spinal levels. Labelled neurons in the nucleus dorsomedialis of the upper spinal cord were thought not to project their axons into the cervical vagus.
为了明确迷走神经的感觉投射和运动起源，在一系列羔羊的颈迷走神经或结状神经节内注射了WGA-HRP和CTB-HRP。在实现预期结果方面，向结状神经节内注射比向颈迷走神经内注射更为成功。前者使孤束（TS）的下行和上行成分均出现标记。下行成分大量终止于孤束核（nTS）的所有同侧和某些对侧亚核以及颈上段脊髓。在三叉神经脊束核的中间亚核内以及颈上段脊髓的I层内也观察到了散在的终末。孤束的上行成分终止于孤束核的吻侧区域、三叉神经主感觉核的特定部分以及外侧臂旁核和 Kölliker-Fuse 核。迷走神经的运动起源几乎完全同侧地起自迷走神经背运动核、疑核以及位于颈上段脊髓水平中间灰质外侧部的迷走后核尾部。上脊髓背内侧核中的标记神经元被认为其轴突不投射到颈迷走神经。
