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贝克威思-维德曼综合征与幼年型纤维腺瘤:一例报告

Beckwith-Wiedemann syndrome and juvenile fibroadenoma: a case report.

作者信息

Poh Melissa M, Ballard Tiffany N, Wendel J Jason

机构信息

Department of Plastic Surgery, Vanderbilt University Medical Center, Nashville, TN 37232-2345, USA.

出版信息

Ann Plast Surg. 2010 Jun;64(6):803-6. doi: 10.1097/sap.0b013e3181b025f6.

Abstract

Beckwith-Wiedemann syndrome (BWS) is a complex overgrowth disorder usually recognized at birth. Children diagnosed with BWS, particularly those with hemihypertrophy, experience an increased risk of developing benign and malignant tumors. This case report presents a 12-year-old girl with BWS and hemihypertrophy who rapidly developed enlarging, asymmetric tumors of bilateral breasts. Few cases of patients with BWS and benign breast tumors exist in the literature. The differential diagnosis of breast tumors in the adolescent female is described. The treatment plan and reconstruction options particular to the developing young female are also discussed.

摘要

贝克威思-维德曼综合征(BWS)是一种通常在出生时就被识别出的复杂过度生长疾病。被诊断为BWS的儿童,尤其是那些患有半身肥大的儿童,患良性和恶性肿瘤的风险增加。本病例报告介绍了一名患有BWS和半身肥大的12岁女孩,她双侧乳房迅速出现不断增大的不对称肿瘤。文献中很少有BWS患者并发良性乳腺肿瘤的病例。本文描述了青春期女性乳腺肿瘤的鉴别诊断。还讨论了针对发育中的年轻女性的治疗方案和重建选择。

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