Klinik und Poliklinik für Augenheilkunde, Klinikum rechts der Isar, Technische Universität München, Ismaningerstrasse 22, Munich, Germany.
J Refract Surg. 2010 May;26(5):314-20. doi: 10.3928/1081597X-20090617-12. Epub 2010 May 19.
The accuracy of intraocular lens (IOL) calculation is limited by the variation of the measurement of corneal power, axial length, anterior chamber depth, and effective postoperative lens position. Therefore, IOL predictability is limited. The aim of this study was to evaluate the performance of the novel light adjustable lens (LAL, Calhoun Vision).
Ten eyes with cataracts (seven patients) were included. After standard phacoemulsification, the LAL was implanted. Two to 3 weeks after surgery, all IOL adjustments had been completed. Preoperatively, pre-adjustment, pre-lock-in, and 1 month post-lock-in, a full ophthalmic examination including objective (autorefraction) and subjective refraction (ie, manifest uncorrected visual acuity [UCVA] and manifest best spectacle-corrected visual acuity [BSCVA]) and topography were performed.
All cataract surgeries were performed with no complications. Two weeks after surgery, the mean refraction was +0.78+/-0.79 diopters (D). After adjustment and lock-in, the refraction was -0.07+/-0.21 D. In 4 of 10 eyes, second adjustments were necessary. One month after surgery, all patients were within +/-0.50 D of the intended refraction. Preoperatively, the cylinder was 0.88+/-0.77 D, but was reduced after adjustments to 0.15+/-0.20 D. Mean UCVA was 1.02, and all eyes gained at least two lines on the Snellen visual acuity test (ie, BSCVA) after surgery.
The LAL is a new IOL with the ability to correct up to 2.00 D of sphere and cylinder after implantation. Our first clinical results are promising and indicate effective safety and stability.
人工晶状体（IOL）计算的准确性受到角膜屈光力、眼轴长度、前房深度和有效术后晶状体位置测量变化的限制。因此，IOL 的预测能力是有限的。本研究旨在评估新型光调节人工晶状体（LAL，Calhoun Vision）的性能。
纳入 10 只白内障眼（7 例患者）。标准超声乳化白内障吸除术后植入 LAL。术后 2-3 周完成所有 IOL 调整。术前、预调整、预锁定和锁定后 1 个月，进行全面眼科检查，包括客观（自动折射）和主观折射（即，明显未矫正视力[UCVA]和明显最佳矫正视力[BSCVA]）和地形图。
所有白内障手术均无并发症。术后 2 周，平均屈光度为+0.78+/-0.79 屈光度（D）。调整和锁定后，屈光度为-0.07+/-0.21 D。在 10 只眼中的 4 只眼需要进行第二次调整。术后 1 个月，所有患者的屈光度均在预期值的+/-0.50 D 以内。术前柱镜为 0.88+/-0.77 D，但调整后降至 0.15+/-0.20 D。平均 UCVA 为 1.02，所有术后视力均提高至少两行（即 BSCVA）。
LAL 是一种新型 IOL，植入后可矫正高达 2.00 D 的球镜和柱镜。我们的初步临床结果很有希望，表明其具有有效的安全性和稳定性。
