Markt B, Bergmann G, Raab W, Willvonseder R
Acta Med Austriaca. 1977;4(4-9):144-8.
A method is given for simultaneous in vivo measurement of mineral and collagen metabolism of the bone. Accretion rates of 47-calcium as a chlorid into the bone are representative for bone mineralisation and of 99m-technetium labelled pyrophosphate for collagen metabolism. Compartmental models used for analysis are presented. Bone accretion rates are given in mg, or mMol respectively per unit time for the skeleton, by computation of the specific activity of 47-calcium and 99m-Technetium pyrophosphate and rational bone accretion as registered by total body profile scanning technique. The results obtained in five normal volunteers are presented.
本文给出了一种同时在体内测量骨骼矿物质和胶原蛋白代谢的方法。作为氯化物的47-钙向骨骼中的沉积率代表骨矿化，而99m-锝标记的焦磷酸盐的沉积率代表胶原蛋白代谢。文中介绍了用于分析的房室模型。通过计算47-钙和99m-锝焦磷酸盐的比活度以及全身轮廓扫描技术记录的合理骨沉积，以每单位时间毫克或毫摩尔为单位给出骨骼的骨沉积率。文中展示了在五名正常志愿者身上获得的结果。
