贝尔法斯特 90 岁以上老人:是先天还是后天?免疫、心血管和遗传因素。

BELFAST nonagenarians: nature or nurture? Immunological, cardiovascular and genetic factors.

机构信息

Department of Geriatric Medicine, School of Medicine, Dentistry and Biomedical Science, Queens University Belfast, Whitla Medical Building, 97 Lisburn Road, Belfast BT9 7BL, Northern Ireland.

出版信息

Immun Ageing. 2010 May 27;7:6. doi: 10.1186/1742-4933-7-6.

Abstract

Nonagenarians are the fastest growing sector of populations across Western European and the developed world. They are some of the oldest members of our societies and survivors of their generation and may help us understand how to age not only longer, but better.The Belfast Longevity Group enlisted the help of 500 community-living, mobile, mentally competent, 'elite' nonagenarians, as part of an ongoing study of ageing. We assessed some immunological, cardiovascular, nutritional and genetic factors and some aspects of their interaction in this group of 'oldest old'.Here we present some of the evidence related to genetic and nutritional factors which seem to be important for good quality ageing in nonagenarians from the Belfast Elderly Longitudinal Free-living Ageing STudy (BELFAST).

摘要

在西欧和发达世界,90 岁以上的老年人是人口增长最快的群体。他们是社会中最年长的成员之一,也是他们那一代人的幸存者,他们的存在可能有助于我们理解如何不仅活得更长,而且活得更好。作为一项正在进行的衰老研究的一部分,贝尔法斯特长寿小组招募了 500 名生活在社区、行动自如、精神健全的“精英”90 岁以上的老年人。我们评估了这组“最年长的老年人”的一些免疫、心血管、营养和遗传因素,以及它们之间的一些相互作用。在这里,我们介绍了一些与遗传和营养因素有关的证据,这些因素似乎对来自贝尔法斯特老年人纵向自由生活衰老研究(BELFAST)的 90 岁以上老年人的高质量衰老很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0ff/2902418/2530b48f1810/1742-4933-7-6-1.jpg

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