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伦敦大学学院的蛋白质注释和建模服务器。

Protein annotation and modelling servers at University College London.

机构信息

Bioinformatics Group, University College London, Gower Street, London, WC1E 6BT, UK.

出版信息

Nucleic Acids Res. 2010 Jul;38(Web Server issue):W563-8. doi: 10.1093/nar/gkq427. Epub 2010 May 27.

DOI:10.1093/nar/gkq427
PMID:20507913
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2896093/
Abstract

The UCL Bioinformatics Group web portal offers several high quality protein structure prediction and function annotation algorithms including PSIPRED, pGenTHREADER, pDomTHREADER, MEMSAT, MetSite, DISOPRED2, DomPred and FFPred for the prediction of secondary structure, protein fold, protein structural domain, transmembrane helix topology, metal binding sites, regions of protein disorder, protein domain boundaries and protein function, respectively. We also now offer a fully automated 3D modelling pipeline: BioSerf, which performed well in CASP8 and uses a fragment-assembly approach which placed it in the top five servers in the de novo modelling category. The servers are available via the group web site at http://bioinf.cs.ucl.ac.uk/.

摘要

UCL 生物信息学组的门户网站提供了多个高质量的蛋白质结构预测和功能注释算法，包括 PSIPRED、pGenTHREADER、pDomTHREADER、MEMSAT、MetSite、DISOPRED2、DomPred 和 FFPred，分别用于预测二级结构、蛋白质折叠、蛋白质结构域、跨膜螺旋拓扑、金属结合位点、蛋白质无序区域、蛋白质结构域边界和蛋白质功能。我们还提供了一个全自动的 3D 建模管道：BioSerf，它在 CASP8 中表现出色，并使用片段组装方法，在从头建模类别中排名前五。这些服务器可通过小组网站 http://bioinf.cs.ucl.ac.uk/ 获取。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6eb9/2896093/135a33cb36e5/gkq427f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6eb9/2896093/e84f6da34aa6/gkq427f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6eb9/2896093/b1b6ad1ae983/gkq427f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6eb9/2896093/7a93715c4881/gkq427f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6eb9/2896093/135a33cb36e5/gkq427f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6eb9/2896093/e84f6da34aa6/gkq427f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6eb9/2896093/b1b6ad1ae983/gkq427f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6eb9/2896093/7a93715c4881/gkq427f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6eb9/2896093/135a33cb36e5/gkq427f4.jpg

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本文引用的文献

[1]
Transmembrane protein topology prediction using support vector machines.

BMC Bioinformatics. 2009-5-26

[2]
pGenTHREADER and pDomTHREADER: new methods for improved protein fold recognition and superfamily discrimination.

Bioinformatics. 2009-7-15

[3]
Jalview Version 2--a multiple sequence alignment editor and analysis workbench.

Bioinformatics. 2009-5-1

[4]
PDBsum new things.

Nucleic Acids Res. 2009-1

[5]
Protein structure modeling with MODELLER.

Methods Mol Biol. 2008

[6]
FFPred: an integrated feature-based function prediction server for vertebrate proteomes.

Nucleic Acids Res. 2008-7-1

[7]
Gene3D: comprehensive structural and functional annotation of genomes.

Nucleic Acids Res. 2008-1

[8]
Data growth and its impact on the SCOP database: new developments.

Nucleic Acids Res. 2008-1

[9]
Computer-assisted protein domain boundary prediction using the DomPred server.

Curr Protein Pept Sci. 2007-4

[10]
Improving the accuracy of transmembrane protein topology prediction using evolutionary information.

Bioinformatics. 2007-3-1

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