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三位一体进化

Trinity Evolution.

作者信息

Rush Shannon M

机构信息

Department of Podiatric Surgery, Palo Alto Medical Foundation, Mountain View, CA, USA.

出版信息

Foot Ankle Spec. 2010 Jun;3(3):144-7. doi: 10.1177/1938640010369643. Epub 2010 Apr 16.

Abstract

Trinity Evolution Cryopreserved Cell Viable Bone Matrix is a minimally manipulated, human cellular, and tissue-based allograft containing adult mesenchymal stem cells, osteoprogenitor cells, and a demineralized cortical component. The cancellous bone used to produce Trinity Evolution is derived from freshly recovered donor tissue by Food and Drug Administration-registered facilities and processed under aseptic conditions. Preclinical in vivo and in vitro testing as well as strict donor screening has demonstrated the safety of Trinity Evolution as well as its osteoinductive and osteogenic potential contained within a natural osteoconductive matrix.

摘要

三一进化冷冻保存细胞活性骨基质是一种经过最少操作的、基于人细胞和组织的同种异体移植物,包含成人间充质干细胞、骨祖细胞和脱矿皮质成分。用于生产三一进化的松质骨来自食品药品监督管理局注册机构新回收的供体组织,并在无菌条件下进行处理。临床前的体内和体外测试以及严格的供体筛选已证明三一进化的安全性及其在天然骨传导基质中所含的骨诱导和成骨潜力。

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