Chung G, Kantor G R, Whipple S
Hahnemann University School of Medicine, Philadelphia, PA.
J Am Acad Dermatol. 1991 May;24(5 Pt 2):832-5. doi: 10.1016/0190-9622(91)70126-m.
We report a case of noduloulcerative tertiary syphilis that had gone misdiagnosed as discoid lupus erythematosus for many years. This case is noteworthy for (1) a Jarisch-Herxheimer-like reaction, (2) a dramatic response to penicillin therapy despite the presence of long-standing disease, and (3) posttreatment granulomas of possible hypersensitivity origin.