异维A酸治疗相关的硬化性黏液水肿的改善

Improvement of scleromyxedema associated with isotretinoin therapy.

作者信息

Hisler B M, Savoy L B, Hashimoto K

机构信息

Dermatology Service, Veterans Administration Medical Center, Allen Park, MI 48226.

出版信息

J Am Acad Dermatol. 1991 May;24(5 Pt 2):854-7. doi: 10.1016/0190-9622(91)70132-l.

DOI:10.1016/0190-9622(91)70132-l

PMID:2050852

Abstract

The treatment of scleromyxedema has been largely ineffective. We report improvement of scleromyxedema with myopathy after treatment with isotretinoin, 40 mg twice a day. We review other therapeutic modalities used for this disorder and discuss properties of isotretinoin that may have contributed to the favorable response.

摘要

硬肿病性黏液水肿的治疗大多无效。我们报告了1例硬肿病性黏液水肿伴肌病患者，经异维A酸每日2次、每次40mg治疗后病情改善。我们回顾了用于该疾病的其他治疗方式，并讨论了可能促成良好疗效的异维A酸的特性。