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硬化性黏液水肿:全身用糖皮质激素治疗的经验及已发表文献综述

Scleromyxedema: An experience using treatment with systemic corticosteroid and review of the published work.

作者信息

Lin Yi-Chiun, Wang Hsi-Ching, Shen Jui-Lung

机构信息

Department of Dermatology, Taichung Veterans General Hospital, Taichung, Taiwan.

出版信息

J Dermatol. 2006 Mar;33(3):207-10. doi: 10.1111/j.1346-8138.2006.00047.x.

Abstract

Scleromyxedema, a rare cutaneous mucinosis of unknown cause, is a variant of generalized papular mucinosis that is also known as generalized lichen myxedematosus. It is characterized clinically by generalized papular or scleroderma-like eruptions. Histopathological examination reveals mucin deposition and a proliferation of fibroblasts in the upper dermis. We describe the case of a man with scleromyxedema treated with systemic corticosteroids whose skin lesions improved gradually within 4 weeks.

摘要

硬化性黏液水肿是一种病因不明的罕见皮肤黏液病,是泛发性丘疹性黏液病的一种变体,也被称为泛发性黏液性苔藓。其临床特征为泛发性丘疹或硬皮病样皮疹。组织病理学检查显示真皮上层有黏液沉积和成纤维细胞增生。我们描述了一例接受全身性皮质类固醇治疗的硬化性黏液水肿男性患者,其皮肤病变在4周内逐渐改善。

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