Center for Health Research, Portland, OR, USA.
Med Care. 2010 Jul;48(7):604-10. doi: 10.1097/MLR.0b013e3181dbdce7.
Although colorectal cancer (CRC) prognosis is improved by early diagnosis, screening rates remain low.
To determine the effect of an automated telephone intervention on completion of fecal occult blood testing (FOBT).
In this randomized controlled trial conducted at Kaiser Permanente Northwest, a not-for-profit health maintenance organization, 5905 eligible patients aged 51 to 80, at average risk for CRC and due for CRC screening, were randomly assigned to an automated telephone intervention (n = 2943) or usual care (UC; n = 2962). The intervention group received up to three 1-minute automated telephone calls that provided a description and health benefits of FOBT. During the call, patients could request that an FOBT kit be mailed to their home. Those who requested but did not return the cards received an automated reminder call. Cox proportional hazard method was used to determine the independent effect of automated telephone calls on completion of an FOBT, after adjusting for age, sex, and prior CRC screening.
By 6 months after call initiation, 22.5% in the intervention and 16.0% in UC had completed an FOBT. Those in the intervention group were significantly more likely to complete an FOBT (hazard ratio, 1.31; 95% confidence interval, 1.10-1.56) compared with UC. Older patients (aged 71-80 vs. aged 51-60) were also more likely to complete FOBT (hazard ratio, 1.48; 95% confidence interval, 1.07-2.04).
Automated telephone calls increased completion of FOBT. Further research is needed to evaluate automated telephone interventions among diverse populations and in other clinical settings.
尽管早期诊断提高了结直肠癌(CRC)的预后,但筛查率仍然很低。
确定自动化电话干预对完成粪便潜血检测(FOBT)的影响。
在 Kaiser Permanente Northwest(一家非营利性健康维护组织)进行的这项随机对照试验中,5905 名符合条件的年龄在 51 至 80 岁、平均 CRC 风险且需要 CRC 筛查的患者被随机分配至自动化电话干预组(n=2943)或常规护理组(UC;n=2962)。干预组接受最多三次 1 分钟的自动化电话,提供 FOBT 的描述和健康益处。在通话过程中,患者可以要求将 FOBT 试剂盒邮寄到家中。那些要求但未返回卡片的人会收到自动提醒电话。使用 Cox 比例风险方法,在调整年龄、性别和既往 CRC 筛查后,确定自动化电话对完成 FOBT 的独立影响。
在电话开始后的 6 个月,干预组有 22.5%的人完成了 FOBT,而 UC 组只有 16.0%。与 UC 相比,干预组完成 FOBT 的可能性显著更高(风险比,1.31;95%置信区间,1.10-1.56)。年龄较大的患者(71-80 岁与 51-60 岁)也更有可能完成 FOBT(风险比,1.48;95%置信区间,1.07-2.04)。
自动化电话增加了 FOBT 的完成率。需要进一步研究来评估在不同人群和其他临床环境中使用自动化电话干预的效果。