与α1-抗胰蛋白酶缺乏症和皮肤血管炎相关的穆尔-托雷综合征。1例免疫抑制治疗期间皮肤肿瘤病情加重的病例报告。

Muir-Torre syndrome associated with alpha 1-antitrypsin deficiency and cutaneous vasculitis. Report of a case with exacerbation of a cutaneous neoplasm during immunosuppressive therapy.

作者信息

Guitart J, McGillis S T, Bergfeld W F, Tuthill R J, Bailin P L, Camisa C

机构信息

Department of Dermatology, Cleveland Clinic Foundation, Ohio.

出版信息

J Am Acad Dermatol. 1991 May;24(5 Pt 2):875-7. doi: 10.1016/0190-9622(91)70137-q.

DOI:10.1016/0190-9622(91)70137-q

PMID:2050856

Abstract

We describe a patient with both Muir-Torre syndrome and alpha 1-antitrypsin deficiency. A keratoacanthoma developed after immunosuppressive therapy for necrotizing vasculitis. To our knowledge, this is the first reported case of Muir-Torre syndrome associated with alpha 1-antitrypsin deficiency.

摘要

我们描述了一位同时患有穆尔-托雷综合征和α1-抗胰蛋白酶缺乏症的患者。在对坏死性血管炎进行免疫抑制治疗后出现了角化棘皮瘤。据我们所知，这是首例报道的与α1-抗胰蛋白酶缺乏症相关的穆尔-托雷综合征病例。