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穆尔-托雷综合征。皮脂腺增生的组织学谱。

Muir-Torre syndrome. Histologic spectrum of sebaceous proliferations.

作者信息

Burgdorf W H, Pitha J, Fahmy A

出版信息

Am J Dermatopathol. 1986 Jun;8(3):202-8. doi: 10.1097/00000372-198606000-00004.

DOI:10.1097/00000372-198606000-00004
PMID:3728878
Abstract

The sebaceous proliferations seen in patients with Muir-Torre syndrome are unique and difficult to classify. Having reviewed over 50 skin biopsies from five patients with Muir-Torre syndrome, we conclude that the primary proliferation involves the hair follicle and most often resembles either a keratoacanthoma or a sebaceous proliferation, but may have histologic features of both lesions. Unusual patterns seen in the sebaceous components may include solid basaloid sheets, mucinous areas, and convoluted glands.

摘要

穆尔-托雷综合征患者中出现的皮脂腺增生具有独特性且难以分类。在回顾了5例穆尔-托雷综合征患者的50余份皮肤活检样本后,我们得出结论,主要增生累及毛囊,最常类似角化棘皮瘤或皮脂腺增生,但可能具有两种病变的组织学特征。皮脂腺成分中出现的异常形态可能包括实性基底样细胞层、黏液样区域和迂曲的腺体。

相似文献

1
Muir-Torre syndrome. Histologic spectrum of sebaceous proliferations.穆尔-托雷综合征。皮脂腺增生的组织学谱。
Am J Dermatopathol. 1986 Jun;8(3):202-8. doi: 10.1097/00000372-198606000-00004.
2
Sebaceous carcinoma of the eyelid in an immunocompromised patient with Muir-Torre syndrome.一名患有穆尔-托雷综合征的免疫功能低下患者的眼睑皮脂腺癌。
Can J Ophthalmol. 1995 Oct;30(6):324-6.
3
Muir-Torre syndrome.穆尔-托雷综合征
Lancet Oncol. 2005 Dec;6(12):980-7. doi: 10.1016/S1470-2045(05)70465-4.
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Ocular Adnexal Adenomatoid Sebaceous Gland Hyperplasia: A Clinical and Immunopathologic Analysis in Relation to the Muir-Torre Syndrome.眼附属器腺样汗管样腺增生:与 Muir-Torre 综合征相关的临床和免疫病理分析。
Ophthalmic Plast Reconstr Surg. 2020 Jan/Feb;36(1):e6-e12. doi: 10.1097/IOP.0000000000001497.
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The Muir-Torre syndrome: a disease of sebaceous and colonic neoplasms.穆尔-托雷综合征:一种皮脂腺及结肠肿瘤疾病。
Dermatologica. 1989;178(1):23-8. doi: 10.1159/000248381.
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[Differential diagnostics of sebaceous tumors].[皮脂腺肿瘤的鉴别诊断]
Pathologe. 2014 Sep;35(5):443-55. doi: 10.1007/s00292-014-1934-y.
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[Keratoacanthoma in co-existence with nevus sebaceus (author's transl)].角化棘皮瘤与皮脂腺痣并存(作者译)
Z Hautkr. 1981 Dec 15;56(24):1585-95.
8
Unusual eyelid tumors with sebaceous differentiation in the Muir-Torre syndrome. Rapid clinical regrowth and frank squamous transformation after biopsy.穆尔-托雷综合征中具有皮脂腺分化的罕见眼睑肿瘤。活检后临床快速复发及明显的鳞状化生。
Ophthalmology. 1988 Nov;95(11):1543-8. doi: 10.1016/s0161-6420(88)32975-1.
9
Muir-Torre syndrome associated with alpha 1-antitrypsin deficiency and cutaneous vasculitis. Report of a case with exacerbation of a cutaneous neoplasm during immunosuppressive therapy.与α1-抗胰蛋白酶缺乏症和皮肤血管炎相关的穆尔-托雷综合征。1例免疫抑制治疗期间皮肤肿瘤病情加重的病例报告。
J Am Acad Dermatol. 1991 May;24(5 Pt 2):875-7. doi: 10.1016/0190-9622(91)70137-q.
10
Muir-Torre syndrome: case report of a patient with concurrent jejunal and ureteral cancer and a review of the literature.穆尔-托雷综合征:一例并发空肠和输尿管癌患者的病例报告及文献综述
J Am Acad Dermatol. 1999 Nov;41(5 Pt 1):681-6. doi: 10.1016/s0190-9622(99)70001-0.

引用本文的文献

1
[Muir-Torre syndrome with previously undescribed frameshift mutation in the MSH2 gene].[伴有MSH2基因中先前未描述的移码突变的穆尔-托综合征]
Hautarzt. 2013 Apr;64(4):290-4. doi: 10.1007/s00105-012-2503-z.
2
Sebaceous neoplasia and Torre-Muir syndrome.皮脂腺瘤形成与托雷-缪尔综合征。
Curr Diagn Pathol. 2007 Aug;13(4):301-319. doi: 10.1016/j.cdip.2007.05.001.
3
Muir-Torre phenotype has a frequency of DNA mismatch-repair-gene mutations similar to that in hereditary nonpolyposis colorectal cancer families defined by the Amsterdam criteria.
穆尔-托雷综合征的DNA错配修复基因突变频率,与依据阿姆斯特丹标准定义的遗传性非息肉病性结直肠癌家族中的频率相似。
Am J Hum Genet. 1998 Jul;63(1):63-70. doi: 10.1086/301926.
4
Sebaceous gland adenoma of the palpebral conjunctiva in a patient with Muir-Torre-syndrome: a case report.
Graefes Arch Clin Exp Ophthalmol. 1994 Dec;232(12):734-6. doi: 10.1007/BF00184276.