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Urinary trypsin inhibitor: miraculous medicine in many surgical situations?尿胰蛋白酶抑制剂：众多手术场景中的神奇药物？
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Effect of ulinastatin on cytokine reaction during gastrectomy.乌司他丁对胃癌根治术围手术期细胞因子反应的影响
Korean J Anesthesiol. 2010 Apr;58(4):334-7. doi: 10.4097/kjae.2010.58.4.334. Epub 2010 Apr 28.
2
The effect of ulinastatin on hemostasis in major orthopedic surgery.乌司他丁对大型骨科手术止血的影响。
Korean J Anesthesiol. 2010 Jan;58(1):25-30. doi: 10.4097/kjae.2010.58.1.25. Epub 2010 Jan 31.
3
Urinary trypsin inhibitors afford cardioprotective effects through activation of PI3K-Akt and ERK signal transduction and inhibition of p38 MAPK and JNK.尿胰蛋白酶抑制剂通过激活PI3K-Akt和ERK信号转导以及抑制p38 MAPK和JNK发挥心脏保护作用。
Cardiology. 2009;114(4):264-70. doi: 10.1159/000234321. Epub 2009 Aug 13.
4
Treatment of patients with severe sepsis using ulinastatin and thymosin alpha1: a prospective, randomized, controlled pilot study.乌司他丁联合胸腺肽α1治疗严重脓毒症患者的前瞻性、随机、对照性初步研究。
Chin Med J (Engl). 2009 Apr 20;122(8):883-8.
5
Urinary trypsin inhibitor protects against liver injury and coagulation pathway dysregulation induced by lipopolysaccharide/D-galactosamine in mice.尿胰蛋白酶抑制剂可保护小鼠免受脂多糖/ D-半乳糖胺诱导的肝损伤和凝血途径失调。
Lab Invest. 2009 Jul;89(7):833-9. doi: 10.1038/labinvest.2009.35. Epub 2009 Apr 27.
6
Impaired liver regeneration with humoral and genetic disturbances in urinary trypsin inhibitor-deficient mice.尿胰蛋白酶抑制剂缺陷小鼠中伴有体液和基因紊乱的肝脏再生受损。
Liver Int. 2009 Aug;29(7):979-87. doi: 10.1111/j.1478-3231.2009.01990.x. Epub 2009 Mar 3.
7
Urinary trypsin inhibitor attenuates hepatic ischemia-reperfusion injury by reducing nuclear factor-kappa B activation.尿胰蛋白酶抑制剂通过减少核因子-κB激活来减轻肝脏缺血再灌注损伤。
Hepatobiliary Pancreat Dis Int. 2009 Feb;8(1):53-8.
8
Effect of pretreatment with high-dose ulinastatin in preventing radiation-induced pulmonary injury in rats.大剂量乌司他丁预处理对预防大鼠放射性肺损伤的作用。
Eur J Pharmacol. 2009 Jan 28;603(1-3):114-9. doi: 10.1016/j.ejphar.2008.12.007. Epub 2008 Dec 10.
9
A new immunomodulatory therapy for severe sepsis: Ulinastatin Plus Thymosin {alpha} 1.一种用于严重脓毒症的新型免疫调节疗法：乌司他丁联合胸腺肽α1
J Intensive Care Med. 2009 Jan-Feb;24(1):47-53. doi: 10.1177/0885066608326970. Epub 2008 Nov 25.
10
Protective effects of urinary trypsin inhibitor on systemic inflammatory response induced by lipopolysaccharide.尿胰蛋白酶抑制剂对脂多糖诱导的全身炎症反应的保护作用。
J Clin Biochem Nutr. 2008 Nov;43(3):139-42. doi: 10.3164/jcbn.2008059. Epub 2008 Oct 31.

Urinary trypsin inhibitor: miraculous medicine in many surgical situations?

作者信息

Han Jong In

机构信息

Department of Anesthesiology and Pain Medicine, School of Medicine, Ewha Womans University, Seoul, Korea.

出版信息

Korean J Anesthesiol. 2010 Apr;58(4):325-7. doi: 10.4097/kjae.2010.58.4.325. Epub 2010 Apr 28.

DOI:10.4097/kjae.2010.58.4.325
PMID:20508786
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2876850/
Abstract
摘要