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[通过生活质量评估对慢性阻塞性肺疾病(COPD)治疗效果的评估:方法学考量]

[Evaluation of therapeutic effect in chronic obstructive pulmonary disease (COPD) by assessment of quality of life: methodological considerations].

作者信息

Antoniu Sabina Antonela, Azoicăi Doina

机构信息

Universitatea de Medicină şi Farmacie Gr. T. Popa Iaşi Facultatea de Medicină, Disciplina de Pneumologie.

出版信息

Rev Med Chir Soc Med Nat Iasi. 2010 Jan-Mar;114(1):20-8.

PMID:20509271
Abstract

Health status represents a tool frequently used for assessment of therapeutic impact of different therapeutic methods in various diseases including chronic obstructive pulmonary disease (COPD). We review the methodology of health status assessment performed with generic and disease or symptoms specific questionnaires Definition of quality of life-related terms, analysis of data from various studies on COPD using health status as an outcome measure was performed. Health status is widely used in studies assessing efficacy of both pharmacological and non-pharmacological therapeutic methods in COPD. In COPD health status can be measured with several generic or specific questionnaires and can be an appropriate efficacy endpoint in therapeutic trials.

摘要

健康状况是一种经常用于评估包括慢性阻塞性肺疾病(COPD)在内的各种疾病中不同治疗方法治疗效果的工具。我们回顾了使用通用问卷以及疾病或症状特异性问卷进行健康状况评估的方法。进行了与生活质量相关术语的定义,并分析了以健康状况作为结果指标的各种COPD研究的数据。健康状况在评估COPD中药理学和非药理学治疗方法疗效的研究中被广泛使用。在COPD中,健康状况可以通过几种通用或特定问卷进行测量,并且可以作为治疗试验中合适的疗效终点。

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