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[Zerebrale Amyloidangiopathie : Cerebral amyloid angiopathy].

作者信息

Block F

机构信息

Neurologische Klinik HELIOS-Kliniken Schwerin, Schwerin, Deutschland.

出版信息

Nervenarzt. 2011 Feb;82(2):202-6. doi: 10.1007/s00115-010-3035-3.

DOI:10.1007/s00115-010-3035-3
PMID:20512481
Abstract

Cerebral amyloid angiopathy (CAA) is defined by the accumulation of β-amyloid in the walls of cortical arteries. The risk factors of CAA include advanced age and the presence of certain alleles of apolipoprotein E. CAA mostly remains asymptomatic, but the classical manifestation is intracerebral hemorrhage. A definite diagnosis can only be made on the basis of histopathological examination. Detection of lobar hemorrhages and lobar microhemorrhages in imaging investigations support the diagnosis of CAA as long as other causes can be excluded.

摘要

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Eur J Neurol. 2010 Jun 1;17(6):823-9. doi: 10.1111/j.1468-1331.2009.02940.x. Epub 2010 Feb 11.
2
Use of antithrombotic drugs and the presence of cerebral microbleeds: the Rotterdam Scan Study.抗血栓药物的使用与脑微出血的存在:鹿特丹扫描研究
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3
Cerebral microbleeds: a guide to detection and interpretation.
脑微出血:检测与解读指南
Lancet Neurol. 2009 Feb;8(2):165-74. doi: 10.1016/S1474-4422(09)70013-4.
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Prevalence and risk factors of cerebral microbleeds: the Rotterdam Scan Study.脑微出血的患病率及危险因素:鹿特丹扫描研究
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Early surgery versus initial conservative treatment in patients with spontaneous supratentorial intracerebral haematomas in the International Surgical Trial in Intracerebral Haemorrhage (STICH): a randomised trial.国际脑出血外科试验(STICH)中自发性幕上脑内血肿患者早期手术与初始保守治疗的随机试验
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