Shon Wonwoo, Ferguson Sara B, Comfere Nneka I
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
Am J Dermatopathol. 2010 Jun;32(4):392-4. doi: 10.1097/dad.0b013e3181c1acaf.
Cutaneous metastasis from Hürthle cell carcinoma of the thyroid is an extremely rare phenomenon. As far as we can determine, there has been only a single case documented. Our patient, a 68-year old man with a history of Hürthle cell carcinoma of the thyroid, had cutaneous nodules in the scrotum and right chin. Histologic and immunohistochemical examinations confirmed the diagnosis of metastatic Hürthle cell carcinoma of the thyroid. To the best of our knowledge, this is the first reported case of scrotal skin metastasis. This case emphasizes the importance of thorough clinicopathologic correlation for any patient with a malignant scrotal cutaneous neoplasm with Hürthle cell or oncocytic differentiation.
甲状腺嗜酸性细胞癌的皮肤转移是一种极其罕见的现象。据我们所知，仅有一例有文献记载。我们的患者是一名68岁男性，有甲状腺嗜酸性细胞癌病史，阴囊和右下巴出现皮肤结节。组织学和免疫组化检查确诊为甲状腺转移性嗜酸性细胞癌。据我们所知，这是首例报道的阴囊皮肤转移病例。该病例强调了对于任何患有具有嗜酸性细胞或嗜酸性变分化的阴囊皮肤恶性肿瘤患者进行全面临床病理相关性分析的重要性。
