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甲状腺乳头状癌甲状腺切除术后30年发生皮肤转移

Skin Metastasis Occurring 30 Years After Thyroidectomy for Papillary Thyroid Carcinoma.

作者信息

Alwhaid Mohammed S, Mhish Olaa, Tunio Mutahir A, AlMalki Salman, Al Asiri Mushabbab, Al-Qahtani Khalid

机构信息

Radation Oncology, King Faisal Specialist Hospital & Research Centre, Riyadh, SAU.

Faculty of Medicine, Alfaisal University College of Medicine, Riyadh, SAU.

出版信息

Cureus. 2022 Feb 13;14(2):e22180. doi: 10.7759/cureus.22180. eCollection 2022 Feb.

Abstract

The skin is an extremely rare site of metastasis from papillary thyroid carcinoma (PTC) and is linked to underlying disseminated malignancy, which reflects a dismal prognosis. We present the case of a 70-years-old Saudi female who presented at our clinic with an eight-month history of two painful and itchy skin nodules over the scalp and the medial aspect of the right arm. She had a history of total thyroidectomy for PTC 30 years prior. Computed tomography-positron emission tomography showed multiple fluorodeoxyglucose avid lung and skeletal metastases. This case highlights the fact that skin nodules in a patient with a history of PTC should be assessed carefully with a high suspicion of skin metastasis to avoid any delay in treatment.

摘要

皮肤是甲状腺乳头状癌(PTC)极其罕见的转移部位,与潜在的播散性恶性肿瘤相关,这预示着预后不良。我们报告一例70岁沙特女性患者,她因头皮和右臂内侧出现两个疼痛且瘙痒的皮肤结节8个月前来我院就诊。她30年前曾因PTC接受甲状腺全切术。计算机断层扫描-正电子发射断层扫描显示肺部和骨骼有多处氟脱氧葡萄糖摄取增加的转移灶。该病例强调,对于有PTC病史的患者出现的皮肤结节,应高度怀疑皮肤转移并仔细评估,以免延误治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2740/8923252/c39990d813f7/cureus-0014-00000022180-i01.jpg

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