Maassarani F, Leroy C, Dekeuleneer R
Department of Surgery, Centre Hospitalier Régional du Val de Sambre, Sambreville, Belgium.
Acta Chir Belg. 2010 Mar-Apr;110(2):225-7. doi: 10.1080/00015458.2010.11680604.
Solitary fibrous tumours (SFT), described for the first time by Klemperer and Rabin in 1931, are uncommon mesenchymal tumours that have been known to mainly affect the pleura and mediastinum. More recently, solitary fibrous tumours affecting other anatomical sites are being increasingly reported. Clinically, these tumours are asymptomatic and are discovered incidentally. Diagnosis is established at pathology by positive staining for CD34. Their prognosis depends on complete surgical resection and lack of histological signs of malignancy. We report here the case of a 63-year-old woman with double localisation of malignant solitary fibrous tumour who underwent complete removal of her lesions. To the best of our knowledge, this observation is the first description of a primary solitary fibrous tumour totally asymptomatic but already metastatic.
孤立性纤维瘤（SFT）于1931年由克莱姆佩雷尔和拉宾首次描述，是一种罕见的间叶组织肿瘤，主要累及胸膜和纵隔。最近，越来越多关于累及其他解剖部位的孤立性纤维瘤的报道。临床上，这些肿瘤无症状，多为偶然发现。病理诊断通过CD34阳性染色确定。其预后取决于手术完全切除以及无恶性组织学征象。我们在此报告一例63岁女性患有双部位恶性孤立性纤维瘤，其病变已被完全切除。据我们所知，该病例是首例关于原发性孤立性纤维瘤完全无症状但已发生转移的描述。
