Division of Respirology, Neurology and Rheumatology, Department of Medicine, Kurume University School of Medicine, Kurume, Fukuoka, Japan.
Acta Neurol Belg. 2010 Mar;110(1):107-9.
We describe a case of recurrent invasive thymoma associated with myasthenia gravis that responded to combined treatment with prednisolone and tacrolimus. The patient suffered from a myasthenic crisis and received methylprednisolone pulse therapy and partial thymomectomy. Low maintenance doses of prednisolone and tacrolimus shrank the size of the invasive thymoma and maintained the patient without any myasthenic symptoms. We stress the usefulness of combined treatment with tacrolimus and prednisolone for invasive thymoma, especially for unresectable tumors.
我们描述了一例与重症肌无力相关的复发性侵袭性胸腺瘤病例，该病例对泼尼松龙和他克莫司联合治疗有反应。患者患有肌无力危象，接受了甲基泼尼松龙脉冲治疗和部分胸腺切除术。低维持剂量的泼尼松龙和他克莫司缩小了侵袭性胸腺瘤的大小，并使患者无任何肌无力症状。我们强调了他克莫司和泼尼松龙联合治疗侵袭性胸腺瘤的有用性，特别是对于不可切除的肿瘤。
